Suggestive Evidence for Causal Effect of Leptin Levels on Risk for Anorexia Nervosa: Results of a Mendelian Randomization Study.

The EWAS reported four novel loci in Europeans: rs62621812 ( p = 8.2 × 10 −8 , after adjusting for BMI p = 2.8 × 10 −12 , ZNF800 , missense), rs379926 ( p = 3.8 × 10 −3 , after adjusting for BMI p = 3.8 × 10 −6 , KLHL31 , missense), rs972283 ( p = 1.1 × 10 −10 , after adjusting for BMI p = 3.8 × 10 −18 , KLF14 , intergenic), and rs2340550 (only nominally significant after adjusting for BMI p = 2.6 × 10 −02 , ACTL9 , missense; not included in MR).

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