Timing of Intervention in Asymptomatic Patients with Aortic Stenosis.

Eur Cardiol · 2021 · PMC8477179 · PMID 34603512

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showed a trend towards a reduction in mortality with early AVR, but no significant difference in cardiac mortality.[ 62 ] The remaining studies found a significant benefit for AVR compared with conservative management, with lower all-cause and cardiovascular mortality rates.[ 2 , 22 , 63 – 65 ] The results of all six meta-analyses are summarised in Table 4 .

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