Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy.

Elecsys t-tau and p-tau181 levels, as well as their ratios with Aβ 1-42 , were also markedly higher in pathology-confirmed AD compared to non-AD dementia (n = 8; all p < 0.001; Figure 1 ) and separated these groups with very high accuracy (AUC 0.94–0.97); differences in Aβ 1-42 levels, however, were only marginally significant ( p = 0.07, AUC [95% confidence interval] 0.71 [0.47–0.96]) ( Figure 2 ).

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