Fetal Sex and Fetal Environment Interact to Alter Diameter, Myogenic Tone, and Contractile Response to Thromboxane Analog in Rat Umbilical Cord Vessels.

Indeed, the decreased response to U46619 is observed in umbilical arteries from male IUGR compared to their control group counterparts ( Figure 8A , Emax 2.06 ± 0.08 vs 2.48 ± 0.14 mN/mm, respectively, p < 0.05, Bonferroni test), while there is an increase in the IUGR female group that however did not reach statistical significance ( Figure 8B , Emax 1.83 ± 0.14 vs 2.11 ± 0.11 mN/mm, respectively).

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