Burden of invasive group B Streptococcus disease in non-pregnant adults: A systematic review and meta-analysis.

In this review, iGBS has been found to be associated to diabetes and obesity, showing an increasing trend in multiannual studies [ 9 ].

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As in, there is an apparent trend (doubling in incidence), but meta-regression won't detect it because of the between-study variation. 7.

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The meta-regression of diabetes and cardiovascular disease covariates on the incidence of iGBS showed a trend of a slight increase in incidence with increasing prevalence of the covariates, although this association was not statistically significant.

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