However, almost half of these 96 genes (43 genes) showed a log 2 fold-change greater than one in the Igf2 dGGCT / Igf2 +/+ contrast but did not reach statistical significance.
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ZBED6 regulates Igf2 expression partially through its regulation of miR483 expression.
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The sentences
We found a highly significant up-regulation of miR483 expression when the ZBED6- Igf2 axis is disrupted in transgenic mice.