NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older Adults.

Although this observation did not reach statistical significance, the majority of the NR-supplemented group (13 out of 20 participants) had an IHL content greater than 5% prior to supplementation, and 9 out of these 13 individuals had a reduced IHL content after supplementation.

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