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Pre-admission interventions (prehabilitation) to improve outcome after major elective surgery: a systematic review and meta-analysis.

BMJ Open · 2021 · PMC8487197 · PMID 34593498

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Subgroup analyses including studies published before or after 2010 did not change any of our findings; effect size and direction were similar for all the interventions and outcomes that could be grouped, although some did not reach statistical significance because of small sample size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.