Surprisingly, Tgm2 –/– / F13a1 –/– double knockout mice showed a trend toward decreased dilatation of the aorta 6 weeks after injury, and this finding was replicated in Tgm2 –/– / F13a1 –/– mice subjected to carotid artery injury.
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Transglutaminase 2 moderates the expansion of mouse abdominal aortic aneurysms.
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