An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia.

Front Pharmacol · 2021 · PMC8491974 · PMID 34621169

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showed a trendno p-value reported

Inflammatory cytokines IL6 and TNFα mRNA levels showed a trend for increased expression at early time-points to end with a significant decrease at 48 h after surgery.

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highly significantno p-value reported

We also discovered that cytokine changes showed highly significant correlations with each other ( Table 3 ).

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