Extract from Dioscorea bulbifera L. rhizomes aggravate pirarubicin-induced cardiotoxicity by inhibiting the expression of P-glycoprotein and multidrug resistance-associated protein 2 in the mouse liver.

Sci Rep · 2021 · PMC8492811 · PMID 34611244

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showed a trendno p-value reported

Combined DB extract and THP treatment showed a trend suggesting that cardiotoxicity could be strengthened by DB supplementation.

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