In the Neapolis cohort, 18.9% of patients carried the rs41291957 A‐allele (AA+GA): this subgroup was associated with a significant reduction in the prevalence of CTO compared to patients homozygous for the G‐allele, despite the higher rate of concomitant diabetes (the correlation with diabetes, which was nominally significant, did not survive multiple‐testing correction).
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rs41291957 controls miR-143 and miR-145 expression and impacts coronary artery disease risk.
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