TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus.

Acta Neuropathol Commun · 2021 · PMC8501605 · PMID 34625123

Europe PMC DOI

hedged sentence

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

a clear trendp = 0.063so close (0.05 < p ≤ 0.1)

There was a clear trend towards an increase in TNFR1 protein levels (Ctrl: 1.08 ± 0.31, AD: 2.18 ± 0.31; p = 0.063), which did not reach significance due to substantial heterogeneity between cases, but no difference in TNFR2 levels (Fig. 5 b, c).

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