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Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and pharmacodynamics in a randomized phase I trial.

Clin Transl Sci · 2021 · PMC8504815 · PMID 33834628

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showed a trendno p-value reported
Although C max showed a trend to slightly decrease under fed conditions (C max‐fed /C max‐fasted : 0.801; 90% CI, 0.638–1.01), a slight increase in AUC last (AUC last‐fed /AUC last‐fasted : 1.30; 90% CI, 1.14–1.47) was observed (Table S2 ).

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