Barely Significant
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Rapid changes in brain estrogen concentration during male sexual behavior are site and stimulus specific.

Sci Rep · 2021 · PMC8505645 · PMID 34635715

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a strong trendno p-value reported
Friedman analyses on the last point of baseline, interaction and post condition revealed a significant effect and a strong trend of change in estrogen concentration across experimental conditions only in the POM group.

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