Moreover, in these four smoking-related CpG sites identified in ER+ breast cancer, only cg25839482 showed a nominally significant effect on ER− breast cancer risk [OR =0.92, 95% CI (0.88–0.96)], but failed to pass the multiple test correction ( q -value = 0.085) ( Figure 2 ).
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Smoking, DNA Methylation, and Breast Cancer: A Mendelian Randomization Study.
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