High Serum Levels of Wnt Signaling Antagonist Dickkopf-Related Protein 1 Are Associated with Impaired Overall Survival and Recurrence in Esophageal Cancer Patients.

In EAC, a strong trend of earlier recurrence could be observed in the high S-DKK1 group with a median of 13 months (95% CI 6.96–19.04 ± S.E. 3.08) compared to patients with low S-DKK1 with a median of 17 months (95% CI 9.95–24.05 ± S.E. 3.60) ( p = 0.064) ( Figure 3 A).

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