In this analysis NRAS mutations alone did not reach statistical significance as an independent factor impacting AML-free survival, however, the combined oncogenic RAS-pathway category including NRAS, KRAS and CBL was statistically significant in a model that only included genetic factors ( 74 ).
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Molecular Pathogenesis of Chronic Myelomonocytic Leukemia and Potential Molecular Targets for Treatment Approaches.
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