DNA Repair and Immune Response Pathways Are Deregulated in Melanocyte-Keratinocyte Co-cultures Derived From the Healthy Skin of Familial Melanoma Patients.

Front Med (Lausanne) · 2021 · PMC8517393 · PMID 34660619

Europe PMC DOI

hedged sentence

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

did not reach statistical significancep = 0.089so close (0.05 < p ≤ 0.1)

We found a significant upregulation of HEPH and significant downregulation of the rest of genes ( BRCA1, CYP2J2, EIF2AK2, IRF9, NMI, OAS1, PARP9, SEMA3D , and STAT1 ) except for RAD51D where the difference that did not reach statistical significance ( p = 0.089; Supplementary Figure 2 ).

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