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Progress feedback in children and adolescents with internalizing and externalizing symptoms in routine care (OPTIE study): study protocol of a randomized parallel-group trial.

BMC Psychiatry · 2021 · PMC8518324 · PMID 34654378

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a negative trendno p-value reported
In case of an unexpected or a negative trend, possible corrective measures should be discussed and the treatment planning should be adapted accordingly.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.