Thermodynamic Stability of G-Quadruplexes: Impact of Sequence and Environment.

Chembiochem · 2021 · PMC8518667 · PMID 33844423

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a clear trendno p-value reported

There are several reports on subtle sequence effects on the stability of intramolecular quadruplexes.[ 58 , 59 , 60 , 61 ] A clear trend correlating sequence with G4 stability is hampered by tertiary interactions in case of longer loops but also by cation dependencies and topological changes in sequence variants.

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