Brain amyloid burden, sleep, and 24-hour rest/activity rhythms: screening findings from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration Studies.

There was a statistical trend toward a higher proportion of ApoE ε4 carriers among the substudy participants than in the overall A4/LEARN samples (47% vs. 35%, p = .072).

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When we used the less conservative, pointwise method of generating confidence intervals, nominally significant between-groups differences were evident across wider temporal intervals.

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