TSPCs are a kind of mesenchymal stem cells derived from tendon tissue which have the potential of self-renewal and multi-directional differentiation [ 3 , 4 ], but because they come from tendon tissue, they express more markers related to tendon differentiation and have a strong trend of tendon differentiation [ 10 , 11 ].
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Adipogenic differentiation was inhibited by downregulation of PPARγ signaling pathway in aging tendon stem/progenitor cells.
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