7 , 17 , 18 , 21 Whereas, maximally adjusted major access site vascular complications became marginally nonsignificant maintaining a comparable effect direction and size (MH-OR, 0.49 [95% CI, 0.24–1.02], I 2 =75%, n=4; 23, 26–28).
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Ultrasound- Versus Fluoroscopy-Guided Strategy for Transfemoral Transcatheter Aortic Valve Replacement Access: A Systematic Review and Meta-Analysis.
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Ultrasound guidance was also associated with reductions in the risk of life-threatening and major, and minor access site bleeding complications but these did not reach statistical significance (MH-OR, 0.52 [95% CI, 0.26–1.04], I 2 =69%, n=6 and MH-OR, 0.67 [95% CI, 0.34–1.31], I 2 =59%, n=5, respectively; Figure 3 ).