Decreased recent adaptation at human mendelian disease genes as a possible consequence of interference between advantageous and deleterious variants.

Conversely, the sweep deficit at disease genes compared to non-disease genes is much less pronounced when restricting the comparison to genes with recombination rates higher than the median recombination rate (1.137 cM/Mb), and remains only marginally significant ( Figure 6 , FPR=0.029).

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