Extracellular Vesicle Proteins and MicroRNAs Are Linked to Chronic Post-Traumatic Stress Disorder Symptoms in Service Members and Veterans With Mild Traumatic Brain Injury.

Front Pharmacol · 2021 · PMC8526745 · PMID 34690777

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only marginally significantno p-value reported

In this study, we observed higher levels of EV IL-6 in those with mTBI and more severe PTSD symptoms, but group comparisons were only marginally significant. miR-1185-1-3p modulates the mRNA levels of GSK3B, which has been linked to peripheral and central inflammatory diseases, and promotes the expression of cytokines such as TNF-α and IL-6 ( Beurel 2011 ; Garcia-Lacarte et al., 2019 ).

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