Although there was no significant difference in growth kinetics between E218A virus and WT virus, the growth of E218A virus showed a trend of slowing down significantly 48 h after infection ( Figures 3D, E ) .
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Methyltransferase-Deficient Avian Flaviviruses Are Attenuated Due to Suppression of Viral RNA Translation and Induction of a Higher Innate Immunity.
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