Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants.

Sci Adv · 2021 · PMC8528426 · PMID 34669468

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did not reach statistical significanceno p-value reported

The soluble S2P ECTO spike elicited the lowest 50% inhibitory dilution (ID 50 ) titers, whereas the soluble S2GΔHR2 spike increased neutralization with a 7.1-fold higher average ID 50 titer, which did not reach statistical significance because of within-group variation.

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