Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure.

Nat Commun · 2021 · PMC8528821 · PMID 34671027

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0130

boldest claim

The sentences

highly significantP = 6.6 × 10 −10actually significant

The step wise reduction in the SVR rate associated with the increase in the number of TOPs present at baseline was highly significant (logistic regression P = 6.6 × 10 −10 ).

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nominally significantP = 0.013actually significant

The reduction in viral load was nominally significant for patients whose virus carried TOPs at sites NS2 119 ( P = 0.013), NS2 132 ( P = 0.018) or NS3 67 ( P = 0.029) relative to those whose virus did not carry the TOPs at these sites.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.