High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments.

Clin Epigenetics · 2021 · PMC8529776 · PMID 34670587

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0800

boldest claim

The sentences

trending towards significancep = 0.07so close (0.05 < p ≤ 0.1)

GRIA4 also showed a decrease in the same samples trending towards significance (exact sign test p = 0.07) (Fig. 6 B).

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borderline significancep = 0.08so close (0.05 < p ≤ 0.1)

MeD-seq and qMSP results for GRIA4 again showed the same trend with borderline significance (r = 0.48, p = 0.08, Additional file 5 : Figure S5).

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