reported that the difference in mRNA and cytoplasmic protein levels of survivin between MIUC samples and healthy controls did not reach statistical significance ( p = 0.06 and p = 0.07 respectively) [ 61 ], However, 68% of MIUC samples had nuclear survivin localization that was not detected in any of the normal bladder tissue samples ( p < 0.001), supporting the immunohistochemical studies in human BlCa [ 63 ].
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Comparative Cancer Cell Signaling in Muscle-Invasive Urothelial Carcinoma of the Bladder in Dogs and Humans.
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