Elucidating Carfilzomib's Induced Cardiotoxicity in an In Vivo Model of Aging: Prophylactic Potential of Metformin.

Int J Mol Sci · 2021 · PMC8537073 · PMID 34681615

Europe PMC DOI

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0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Concerning the molecular signaling, Cfz upregulated eNOS expression, decreased AMPKα phosphorylation ( Figure 3 C,D), and showed a trend of increase in Akt expression versus controls ( p = 0.08).

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