Leptin Receptor (rs1137101) and Brain-Derived Neurotrophic Factor (rs925946) Gene Variants Are Associated with Obesity in the Early- but Not in the Late-Onset Population of Hungarian Psoriatic Patients.

However, the association of rs2060713 polymorphism and psoriasis vulgaris showed a trend in males with only the early-onset type of psoriasis and in females with the late-onset type of the disease [ 39 ].

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While the proportion of patients with normal weight was significantly less in subjects with two risk alleles (GG genotype) than in the group of patients with two wild alleles (AA genotype (*)), the proportion of obesity was higher in the case of the GG genotype compared to the AA genotype (based on 95% confidence intervals, the difference was borderline significance (#)).

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