1-MNA Ameliorates High Fat Diet-Induced Heart Injury by Upregulating Nrf2 Expression and Inhibiting NF-κB <i>in vivo</i> and <i>in vitro</i>.

TC also decreased but the results did not reach statistical significance ( Figure 5C ). 1-MNA Influenced Oxidative Stress and Inflammation in the HFD-Fed Mouse Heart The IκB degradation is a key step in NF-κB activation, as it allowed NF-κBp65 to be transported from the cytoplasm to the nucleus.

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