A dynamic microscale mid-throughput fibrosis model to investigate the effects of different ratios of cardiomyocytes and fibroblasts.

Lab Chip · 2021 · PMC8547330 · PMID 34545378

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an increasing trendno p-value reported

Higher percentages of fibroblasts corresponded also to an increasing trend in the expression of Col3a1 , Col1a1 , Fn (fibronectin), Mmp2 and Tnc at the mRNA level (Fig.

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a clear trendno p-value reported

S7b † ) but, overall, the presence of an increasing number of CMs did not modulate the proliferative capacity of FBs with a clear trend.

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