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Development of a novel humanized mouse model for improved evaluation of in vivo anti-cancer effects of anti-PD-1 antibody.

Sci Rep · 2021 · PMC8548333 · PMID 34702924

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In HCC827, there was a substantial increase of both CD4 + and CD8 + T-cell infiltration, although it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.