A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas.

Mice bearing the classical primary JX14P tumor also showed a trend toward improvement (p = 0.0858) and although it’s TMZ-resistant counterpart showed no improvement in median survival over TMZ, three long-term tumor-free survivors were noted (Fig. 3 a).

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