While the aggregate enriched species showed a twofold elevation in biotin-labeled tau residence time in the brain post-injury (1.25 ± 0.72) compared to r-sham (0.54 ± 0.20), this value did not reach statistical significance ( p = 0.20) (Fig. 1 B).
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Influence of traumatic brain injury on extracellular tau elimination at the blood-brain barrier.
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