Racial disparity in prostate cancer in the African American population with actionable ideas and novel immunotherapies.

Specifically, they compared ERG rearrangement, SPINK1 overexpression, PTEN deletion, and SPOP mutation, and found, for AA men, ERG rearrangements were significantly less (27.6% vs 42.5%), SPINK1 overexpression was significantly higher (23.4% vs 8.2%), and reductions in PTEN deletion and SPOP mutations approached significance (6.9% vs 19.8% and 4.5% vs 10.3%, respectively). 6.

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