Barely Significant
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Further Investigation of Synaptic Vesicle Protein 2A (SV2A) Ligands Designed for Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging: Synthesis and Structure-Activity Relationship of Substituted Pyridinylmethyl-4-(3,5-difluorophenyl)pyrrolidin-2-ones.

ACS Omega · 2021 · PMC8552234 · PMID 34722967

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a clear trendno p-value reported
The Effect of Halogens Substitution of the pyridinyl 3-methyl group on racemic SynVesT-1 with halogens resulted in a clear trend with respect to affinity.

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