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Carboxypeptidase N1 is anticipated to be a synergy metrics for chemotherapy effectiveness and prognostic significance in invasive breast cancer.

Cancer Cell Int · 2021 · PMC8555242 · PMID 34711246

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a decreasing trendno p-value reported
In contrast, CA153 does not exist in hepatocytes, therefore, it shows a decreasing trend during chemotherapy.

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showed a trendno p-value reported
The prolongation of chemotherapy and long-term liver injury lead to a decrease in CPN1 synthesis and secretion into the blood by hepatocytes, and in summary, CPN1 showed a trend of first increasing and then decreasing.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.