Barely Significant
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Comparison of clinical manifestation of dengue fever in Bangladesh: an observation over a decade.

BMC Infect Dis · 2021 · PMC8555248 · PMID 34715814

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an increasing trendno p-value reported
An increasing trend in GIT features and decreasing trend in hemorrhagic manifestations was noted over the last decade of dengue outbreaks.

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a negative trendno p-value reported
While a negative trend in hemorrhagic manifestations (skin rash, melena, and conjunctival hemorrhage/hemorrhagic sclera) and arthralgia/joint pain were found.

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.