Shaping modern human skull through epigenetic, transcriptional and post-transcriptional regulation of the RUNX2 master bone gene.

6 a); also RUNX2-AS1 levels showed an increasing trend during osteogenic differentiation (Fig. 6 b).

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The expression levels measured during the osteogenic induction were variable across the replicates and it was not always possible to identify a clear trend of activation/silencing during the osteogenesis process (Fig. 7 c–h).

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