The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation.

Nat Commun · 2021 · PMC8556235 · PMID 34716325

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showed a trendno p-value reported

Several additional serine proteases, HTRA3 (high-temperature requirement A serine peptidase 3), DPP7 (dipeptidyl-peptidase 7), FAP (fibroblast activation protein alpha), were upregulated in human scars (Figure S6 ), and also showed a trend in mouse scars.

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