Interestingly, the percentage of dextramer + effector/memory CD8 + T cells producing IFN-γ or GM-CSF (but not TNF) showed a trend for a positive correlation with the cumulative disease score (Fig. 2F ).
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CD8<sup>+</sup> T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis.
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