The Effect of Goal-Directed Fluid Therapy versus Standard Fluid Therapy on the Cuff Leak Gradient in Patients Undergoing Complex Spine Surgery in Prone Position.

On the contrary, patients who received GDFT in the study by Bacchin et al had significantly lesser blood loss as compared with controls. 13 This difference could be due to the variable spine pathology and surgical experience of different surgeons in our study. In our study, there was a decreasing trend in the use of intraoperative fluid in the GDFT group which however did not reach statistical significance probably due to the transfusion of less volume of fluid in both groups.

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