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Inflammatory markers and incident heart failure in older men: the role of NT-proBNP.

Biomark Med · 2021 · PMC8559131 · PMID 33709785

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In age-adjusted Cox proportional hazard models, there were trends toward increased incident HFpEF risk at higher quartiles of CRP (HR 2.28 for third vs first quartile; 95% CI: 0.93–5.61) and IL-6 (HR 1.54 for first vs fourth quartile; 95% CI: 0.67–3.53), although these did not reach statistical significance possibly due to the small number of HFpEF cases (n = 46).

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