Mice from a BALB/c background showed a trend toward reduced bone metastasis following administration of Zol, and this was independent of oestradiol concentrations, a functional adaptive immune system, or tumour (human MDA-MB-231 or mouse 4T1).
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Oestradiol Contributes to Differential Antitumour Effects of Adjuvant Zoledronic Acid Observed Between Pre- and Post-Menopausal Women.
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