Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL.

Also, for the women-only primary analysis, the rs77186623 in LOC105375745 locus associated with HIPadjBMI (β = −0.006, P = 1.74 × 10 −7 ) exhibited nominally significant interaction by background group ( I 2 = 55.3%, P diff = 0.042) and was GWS in the Caribbean group ( N = 3231, MAF = 0.041, β = −0.0078, P = 3.05 × 10 −8 ) but not significant in the mainland group ( N = 4216, MAF = 0.008, β = −0.0015, P = 0.567, Supplementary Material, Table S7 ).

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