Microbiome-Specific Statistical Modeling Identifies Interplay Between Gastrointestinal Microbiome and Neurobehavioral Outcomes in Patients With Autism: A Case Control Study.

Intriguingly, all the taxa that were enriched in the ASD group, including Phyllobacterium , Enterobacteriaceae and Escherichia/Shigella , followed a decreasing trend of ASD > first-degree relative control > healthy controls.

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Overall, the ASD group showed higher trends in GI severity total score, prevalence of food/skin allergy, as well as scores related to restricted eating behavior, although the differences did not reach statistical significance when compared to other groups.

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